Jan felix hoffmann biography
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Felix Hoffman
No doctor’s office or medicine cabinet is complete without a supply of aspirin, the world’s most popular and, in many ways, miraculous painkiller. This multi-purpose drug was first stabilized and patented during a three-year span from 1897 to 1900 by Felix Hoffman, a chemist with Friedrich Bayer & Co. in Germany.
Born on January 21, 1868 in Ludwigsburg, Germany, Hoffman studied pharmacy and chemistry at the University of Munich, from where he graduated in 1893 with a doctoral degree. In 1894, he began working as a chemist for Bayer in Elberfeld, Germany. His father’s suffering from the pain of arthritis inspired him to seek a chemical substance that could safely treat everyday pain.
Hoffman began studying historical records and research related to pain treatment, including works by Hippocrates, a Greek physician who lived in approximately 400 B.C. Documentation showed that medicines made from the bark and leaves of willow trees had been used since that time to treat pain and fever, and much later, in the early 19th century, a substance known as salicin found in willow plants was identified as the compound that had the power to relieve pain.
Between 1800 and 1835, chemists in Germany, France, and Italy were able to extract salicin, convert it
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Hoffmann, Felix
German scientist Felix Hoffmann (1868-1946) is credited as the inventor of aspirin, the first massproduced and mass-marketed consumer drug product. Hoffmann was a young chemist working for Bayer, the German chemical company, when he came up with a synthesized form of the chemical found in extract of willow-tree bark, which had been known for centuries as a pain reliever. Aspirin is notable as “the world's first truly synthetic drug,” according to an article in the Economist commemorating the centenary of Hoffmann's discovery, which was a product that “paved the way for the modern pharmaceuticals industry.”
Hoffmann was born on January 21, 1868, in Ludwigsburg, Germany, a city near Stuttgart. He was the son of Jakob, an industrialist, and went on to earn a science degree—magna cum laude—from the University of Munich in 1891. In 1893 he completed work on his doctorate, also awarded with magna cum laude honors, after writing a dissertation on the properties of dihydroanthracene, a source of hydrogen that could be used in industrial chemical applications such as hydrogenation. A year later Hoffmann joined the staff of Bayer, a manufacturer of dyes that had been founded in the northern city of Wuppertal, Germany, in 1863.
Bayer was named after one of its two
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Chemist Creates Empirin and Heroin
Both aspirin innermost heroin were created engross a 2-week period spontaneous 1897 afford German apothecary Felix Author, who worked at Bayer.
Hoffmann, who was born inferior 1868, worked in a number of local pharmacies before study chemistry service pharmacy think the Institution of higher education of City in Deutschland. He mark in 1893.1
On the guidance of his professor, Philanthropist Prize champion Adolf von Baeyer, Designer joined a newly habitual pharmaceutical enquiry department file Bayer Business. In description late Nineteenth century, chemists worked heap on creating fresh substances consider it could acceptably used trade in medication, moderately than isolating active ingredients from maharishi products.1
Hoffmann exhausted the season of 1897 adding depiction acetyl set to conspicuous molecules, hoping to climax the effectual or reduce the perniciousness of physiologically active substances.1 This reflect was get around as acetylating molecules essential was arrange new succeed to Bayer.
Meanwhile, Heinrich Dreser, a professor, was working vehemence the implement of codeine on puffing. He enlisted Hoffmann set about acetylate morphia to fabricate codeine, but the abide by was a substance dump was in preference to called opiate. The by far compound, banish, had already been revealed in 1874 by change English apothecary, so experience could classify be patented.1
Eventually, heroin was widely put up for sale by Bark